Bupropion improves biochemical parameters of ethanol exposure in rats
نویسندگان
چکیده
Günümüzde alkol alımı sindirim sistemi hastalıkları başta olmak üzere birçok hastalığın önemli bir etkenidir. Dopamin agonistlerinin kaynaklı hasarlar üzerinde iyileşmeye yardımcı olduğunun bilinmesine karşın, bupropionun etanol değişen biyokimyasal parametreler üzerindeki etkileri tam olarak açıklığa kavuşturulmamıştır. Bu çalışma uygulaması ile bazı etkisini değerlendirmek için gerçekleştirildi. Çalışmada ratlara haftada iki kez dört hafta süreyle % 56 yapıldı ve sonrasında bupropion 30 60 mg/kg dozlarda yedi gün oral uygulandı. Çalışma sonunda aspartat aminotransferaz (AST), alanin (ALT), alkalin fosfataz (ALP), üre, kreatinin, total protein glukoz değerlerini tersine çevirdiği belirlendi. bulguları parametreleri etkili şekilde iyileştirdiğini göstermiştir.
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ژورنال
عنوان ژورنال: Kocatepe veteriner dergisi
سال: 2021
ISSN: ['1308-1594']
DOI: https://doi.org/10.30607/kvj.953612